Disease Severity Based on Autologous Serum Skin Test Result in Chronic Spontaneous Urticaria Patients at Dermatology and Venereology Outpatient Clinic of Dr. Mohammad Hoesin General Hospital Palembang

Abstract

Studies on the severity of chronic spontaneous urticaria based on the results of the
Autologous Serum Skin Test (ASST) have been done before, but the results vary so there
are still differences of opinion among some researchers. This study aims to determine
the correlation between disease severity and ASST results in chronic spontaneous
urticaria patients at the Dermatology and Venereology (DV) Polyclinic of Dr. Mohammad
Hoesin (RSMH) Palembang. The type of this study is analytic observational with cross-
sectional design which used secondary data in the form of medical records. There were
110 samples of chronic spontaneous urticaria patients at the DV clinic and it is 76
samples that met the inclusion criteria. The highest distribution of chronic
spontaneous urticaria patients was in the 17-25 year age group (23.7%) and the female
group (64.5%). The majority of chronic spontaneous urticaria patients had negative
ASST results (52.6%) and mild disease activity (63.2%). Bivariate analysis showed no
significant correlation between urticaria activity (UAS7 score) and ASST results with a
value of p = 0.287 or p > 0.05.